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Drug-free nasal spray as a barrier against SARS-CoV-2 and its delta variant: in vitro study of safety and efficacy in human nasal airway epithelia

These outcomes align with findings in emerging research

Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a key transcription factor upregulating the antioxidant response element (ARE)-mediated expression of antioxidant and detoxifying enzymes, and the Nrf2-antioxidant pathway is critical in host defense against acute lung injury (ALI) 24

IV therapy ensures 100% bioavailability, bypassing digestive degradation

Differential expression (DE) analysis between AD- and Iso-cBOs detected genes that were significantly different (Fig